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ABSTRACT Bioaccumulation of butachlor in plants following its application in the farm against weeds was evaluated using Phaseolus vulgaris (bean plant). Also, the risk of the consumption of such plants with some amount of bioaccumulated butachlor by non-target humans was studied using rabbits as animal model. The field experiments were carried out by crop cultivation with the application of 4.0 liters per hectare (2.6 kg a.i/ha), 4.4 liters per hectare ...

ABSTRACT Three fungi isolates were obtained from soil collected from a laundry waste water disposal site. These organisms were identified morphologically as Aspergillus niger, Aspergillus nidulans and Trichoderma hazianum. Ten days pilot study on these organisms indicated that A. nidulans produced α-amylase of highest activity on day 6 and was therefore chosen for further studies. The internal transcribed spacer (ITS) region of the organism showed an amplicon size of approximately ...

ABSTRACT Ficuscapensis leaves have always played a great role in preventing, controlling and alleviating various disease conditions. This study was aimed at validating the traditional use of the leaves of Ficuscapensisin  folk  medicine  as  an  anti-  ulcer  and  immunostimulatory agent.  Diclofenac sodium (100mg/kg)  body weight  was administered intraperitoneally to  induce ulcer.  Seven groups(five rats each)were used. Groups 2(150mg ranithidine),4,5,6and7 served as the ulcer test groups while  group1 and  3  served ...

ABSTRACT In  the   present   study,   the  phytochemical   composition,   immunomodulatory,   leukocyte mobilization,  haematological  and antihepatotoxic  effects of the aqueous  extract of Senna mimosoides leaves were evaluated. The study also covered the effect  of the extract on the activity of lactase and the assessment of the damaging effect of carbon tetrachloride (CCl4) and ameliorative effect of the extract on liver tissue using histopathological technique. This study was aimed at validating the traditional ...

ABSTRACT The aim of this study was to investigate the effects of thiamine, pyridoxine and biotin on the concentrations of blood glucose, serum electrolytes and renal functions of alloxan-induced diabetic rats. A total of twenty seven (27) adult male albino rats of Wistar strain weighing between 160-200 g were used for the study. Twenty four (24) of the animals were rendered diabetic by a single and freshly prepared alloxan monohydrate ...

ABSTRACT A comparative  study of the  effects  of aqueous  extract  of Moringa  oleifera  and  Vernonia amygdalina on selected biochemical indices of prostate pathologies of male  albino rats was investigated  using thirty two  adult male albino  rats of average  weight  of 152g.  Rats were randomly assigned into four groups of eight rats each with different recognizable codes. Group one served as the control and each rat in this group received orally ...

ABSTRACT One of the greatest challenges facing the societies today is the increased emission of greenhouse gas from fossil fuel combustion, with consequent change in climatic conditions. Hence the need for cleaner and renewable energy source. This study was carried out to produce biomethane from fresh cassava wastewater in a liquid phase biodigester. Fresh cassava wastewater (FCWW) (1000 ml) was charged into 5 liter capacity fixed bed bioreactor and were ...

ABSTRACT This study ascertained the wound healing potential of Newbouldia laevis root-bark in experimentally induced leukopenia in rats using excision wound model. 5-Flourouracil (12 mg/kg.b.w) was administered intraperitoneally for three (3) consecutive days after which a maintenance dose of (6 mg/kg.b.w) was administered every four (4) days. The methanol extract, ethyl acetate and methanol fractions of Newbouldia laevis root-bark (0.2 and 0.4 % w/w) were formulated into ointment and applied ...

ABSTRACT Stephania dinklagei is used extensively in South East Nigeria for the traditional treatment of malaria and other associated ailments in form of decoction, in which unspecified quantities are usually consumed without due regards to toxicologic and  other adverse effects. In this study,  the  phytochemicals  were  assessed  as  well  as  the  effects  of  the  antioxidant  and toxicologic properties of methanol leaf extract of  stephania dinklagei in Wistar albino rat. The ...

ABSTRACT The  study  sets-out   to  investigate   the  amount   of  some  selected   class  of  polyphenols   with cardiovascular  benefits,  present  in red wine.  The total phenolic  content of the freshly opened red wine samples  as determined  by Folin-Ciocalteau  Method  (FCM)  were  in the range  of 42-1625 mg/1 Gallic Acid Equivalents  (GAE) (Mean= 1084.6).  Samples J and N,  which were of Spanish and  Portuguese   origins,  respectively,  contained  the  highest  concentration   of  1625   mg/1 ...

ABSTRACT Lipids  and  lipoproteins are  essential  constituents of the  body and  their  activities  assist  in maintenance of the body homeostasis. Sedentary lifestyle, as predisposed by sedentary work has been shown to lead to inactivity which could lead to lipid disorders during pregnancy. Physical activity during pregnancy can reduce the risk of pregnancy induced hypertension and preeclampsia. The present study was designed to ascertain the difference in lipid profile and some ...

ABSTRACT The  effect   of  three  antibiotics   (ciprofloxacin,   lincomycin   and  erythromycin)   on   the inflammatory process was studied both in vitro and in vivo. Agar-induced rat paw oedema was used as a model for acute inflammation, and the antibiotics were administered (10 mg/kg, 20 mg/kg and 40 mg/kg per orally) 1hour before injection of agar. Ciprofloxacin showed a dose- dependent inhibitory effect on the paw oedema though the maximum concentration (40 mg/kg ...

ABSTRACT Diabetes mellitus produces a lot of highly reactive oxygen species which have been attributed to the aetiology and pathophysiology of the disease. In view of the adverse effects associated with synthetic drugs and natural medicine being considered to be safer, cheaper and more effective, traditional antidiabetic plants can be explored. The results of the experiment showed that there were significant increases (P<0.05) in the concentrations of total cholesterol, low ...

ABSTRACT The biphasic pharmacological activity of the aqueous methanol extract of Ricinuscommunisseeds on smooth muscles was investigated in this research. The qualitative and quantitative phytochemical analysis for bioactive compounds in the methanol extract of the fermented and unfermented Ricinuscommunisseeds were carried out by the method of Trease and Evans  and Harborne. The median lethal doses of the two forms of extracts were determined by the method described by Lorke.The qualitative ...

ABSTRACT Haemocyanin is a high molecular weight, dioxygen, transport, copper-glycoprotein with a di- copper active site  found  in the  haemolymph of several marine and  terrestrial invertebrates belonging  to  the  phyla  Mollusca  and  Arthropoda.  Haemocyanin  exists  in  two  distinct conformers:  the  T-conformer  (Tense)  and  the  R-conformer  (Relaxed).Knowledge  of  the molecular architecture around the copper atoms in the active site of haemocyanin is important in understanding how  these  proteins reversibly bind  oxygen. ...

ABSTRACT This research sets out to examine the role of the Nigerian communication commission in regulating the Nigerian telecommunication sector. It further scrutinizes the legal and regulatory framework surrounding the business of telecom industry in Nigeria. It predominantly scrutinizes the provision of the law establishing the National regulator vis a vis other laws establishing the institutional framework, the service providers and the consumers of these telecom services. Such laws as ...

ABSTRACT ABSTRACT Malaria caused by plasmodium parasite is one of the leading infectious diseases in the tropics including Nigeria. Efforts are on to developing more potent antimalarials from plant sources that will be cheaper, without adverse effects, readily available and will be able to replace existing antimalarials that are already facing resistance by plasmodium. Vitex doniana is a medicinal plant used in many part of Nigeria for the treatment of ...

ABSTRACT Three fungal isolates (FSP1, FSP2 and FSP3) were isolated based on morphological characteristics from laundry waste water disposal site. A 10 day pilot study on the three isolates in submerged fermentation system using olive oil as sole carbon source revealed that FSP1 had the highest lipase production on day 9 and pH 4.0 was the optimum pH for the enzyme production. Molecular studies on the ribosomal DNA of FSP1 ...

ABSTRACT The effect of the methanol extract of Jatropha tanjorensis leaves on haematological and antioxidant parameters of rats was investigated. From the study, the percentage yield of the extract  was 9.77%. The qualitative and quantitative phytochemical screening of the extract revealed the presence of active principles such as tannins (69.91±7.53 mg/100 g), flavonoids (3116.15±143.24 mg/100 g), total phenolics (12.98±1.02 mgGAE), steroids (26.17±0.09 mg/100g), terpenoids (208.80±48.31 mg/100 g), alkaloids (1677.78±41.95 mg/100 ...

ABSTRACT This study was carried out to screen, partially purify and characterize Manganese peroxidase from Rigidoporuslignosus. This study started with the optimization of enzymes production in the laboratory scale of submerged fermentation system.A pilot study was carried out for eight days to determine the day of highest Manganese peroxidase activity of which Day 7 wasthe highest. The optimal yield of Manganese peroxidase (0.888 U/ml) was found to be produced under ...