Download Category: BIO-CHEMISTRY PROJECT TOPICS

ABSTRACT This study investigated the effects of home (community) and hospital management of childhood malaria on the prevalence, haematology, biochemical and nutritional indices of malaria parasite infected children in Anambra State, Nigeria. It also evaluated the knowledge, attitude and perceptions of mothers/caregivers about childhood malaria and their home management practices. A total of 248 children between the ages of 0 – 14.9 years and 653house holds randomly sampled were involved ...

ABSTRACT Local production of ash-derived alkali was assessed in this review. Detailed information on local production of ash-derived alkali is rare in literature. Hence, the technology, materials, probable criteria for selection of materials, processes, uses, of alkali were assessed. The project work was carried out in TUDAKA, environmental consultants limited, Ekpan Warri to produce alkali from Cocoa pod husk, plantain peels and palm fruits bunch. The plantain peels was collected ...

ABSTRACT This research work assessed the hypoglycaemic effect of canavaelia ensiforoms and its relationship with serum lipids (total cholesterol, HDL – cholesterol and LDL – cholesterol) in an alloxan induced diabetic rat. Diabetes was induced using 100mg/kg during weight of a 5% stock solution of alloxan. Three were four groups and they were divided into group treated with 200mg/kg body weight of the plant extract, group treated with 400mg/kg body ...

CHAPTER ONE 1.0INTRODUCTION 1.1 BACKGROUND It has been reported that infectious diseases account for one-half of all deaths in the tropicalcountries (WHO, 1977). As a result, people of all continents have long applied poultice and imbibed infusions of indigenous plants dating back to prehistory for health purposes and is still in use today (Sofowora, 1993). Plant medicine (Phytomedicine) has been used in healthcare delivery in many parts of Africa and ...

ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva adansonii were collected from Asata village in Enugu State. The cuttings were authenticated at the Bioresource development centre. They were ...

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap water. Group II rats were fed with fat diet (cow‟s brain) (3.6g/day) ...

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats were divided into four groups Group I: rats were fed a standard Laboratory diet (groups match) ...

ABSTRACT  Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants (Ryan & Majno, 1983). The urgency generated by increased rate of stroke, atherosclerosis attribute due to prolonged use of cyclooxygenase-1 and Cyclooxygenase- 2 inhibitors have accelerated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research (Ryan & Majno, 1983). Attention increasingly has been directed ...

ABSTRACT Wistar albino rats, numbering thirty five (35), were nurtured in the animal house of University of Nigeria Enugu Campus and used for this work. This work is designed to determine the presence of prion (PrP) in Wistar albino rats and the possible changes that sleep deprivation can cause in PrP and fertility hormones. Twenty four (24) of the animals (15 females 9 males) were successfully sleep-deprived for 14 days ...

ABSTRACT This work was aimed at finding the effects of alcohol on some biochemical parameters. A total of one hundred and eighty (180) apparently healthy, non-hypertensive male alcoholics were used for the study. Forty (40) non-consumers of alcohol were used as control. The activity of alanine aminotransferase (ALT) in the control was 10.50±2.00 IU/L while it was 16.50±1.50 IU/L; 17.50±2.00 IU/L and 18.31±2.00 IU/L in alcoholics who showed preference for ...

ABSTRACT Globally, the estimated incidence of diabetes and projection for the year 2030 as given by the International Diabetes Federation (IDF) is 350 million. Kigelia africana is highly used for ethno medicinal purposes although there is paucity of scientific information on its use. This work was therefore, aimed at evaluating the anti-diabetic and antioxidative potential of the plant. Ethanol, methanol and n- hexane extracts of the leaves of Kigelia Africana were used for the ...

ABSTRACT In the present study, the phytochemical composition, immunomodulatory, leukocyte mobilization, haematological and antihepatotoxic effects of the aqueous extract of Senna mimosoides leaves were evaluated. The study also covered the effect of the extract on theactivity of lactase and the assessment of the damaging effect of carbon tetrachloride (CCl4) and ameliorative effect of the extract on liver tissue using histopathological technique. This study was aimed at validating the traditional use of S. mimosoides leaves in ...

ABSTRACT The immuno-modulating effects of leaf extracts of Telfairia occidentalis (Hook F) and Tectona grandis (Linn) on both humoral and cell mediated immune responses were evaluated in vivo.The responding cells were defined by flow cytometry and secretion of various cytokines by ELISA. Structural elucidation of the bioactive molecules responsible for the observed effect was equally attempted. Results of the quantitative phytochemical analyses of the extracts revealed abundance of bioactive compounds such as soluble carbohydrates (1.624 ± ...

ABSTRACT The nutritive and antinutritive compositions of S. dulcificum pulp were analysed to augment the available information on the anti-diabetic effect of the plant. Biochemical parameters like liver function enzymes (ALT, AST, ALP) and bilirubin concentrations,serum total protein, serum albumin and globulin, kidney function parameters (creatinine and urea concentrations), blood glucose, serum lipid profile and lipid peroxidation were determined in rats that were administered different concentrations of the methanolic extract to ascertain ...

ABSTRACT This study was aimed at investigating biochemical changes associated with benign prostatic hyperplasia in ageing men attending clinic at the university of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu State, Nigeria. The assessment included 50 men with BPH attending clinic in addition to 50 healthy men (control). All samples were divided into 5 groups and with varying age ranges (Group 1: Normal control, Group 2: BPH patients ≤ 60 years, on ...

ABSTRACT The sugar and mineral levels of industrially processed fruit juices (mainly 100% and 50% fruit juices) sold to consumers in Enugu state, Nigeria were determined and compared with that of freshly prepared fruit juices. The liquid nature as well as the versatility of juice has increased the ease with which fruit juices can be altered with sugar, contaminants, water or inferior juices by unethical suppliers. This research was performed ...

ABSTRACT Egg consumption is a popular choice for good nutrients, but by far the egg most often consumed by human is the chicken egg, typically unfertilized. Quail eggs help treat tuberculosis, asthma, and diabetes and it can also help prevent kidney, liver, or gallbladder stones. Thus, this study is aimed at determining quail egg’s dietary effect on the blood sugar and lipid profile of alloxan induced diabetic rats. The quail ...

ABSTRACT The high prevalence, complications and cost of conventional drugs in the management diabetes necessitated the search for alternative treatment. As a result, this study seeks to evaluate the composition, anti-diabetic potential toxicity and tissue-protective effects of both the water and methanolic extracts of Persea americana (avocado pear) seed on alloxan-induced diabetic albino rats were investigated. This study was conceived and designed based on information on the local use of ...

ABSTRACT Preservation of fish by drying over different types of heat regimes have been known. However, there has not been a comprehensive comparison in terms of the possible contamination associated with these drying regimes. This work was set to evaluate the levels of PAHs that are likely to accumulate in the bodies of fresh water fishes dried under heat from charcoal, sun (sun drying), electric oven and polythene augmented drying ...

CHAPTER ONE INTRODUCTION The genus Indigofera Linn. is a large genus of about 700 species of flowering plants belonging to the sub-family Papilionoideae in the family Fabaceae / Leguminosae. They occur throughout the tropical and subtropical regions of the world. Burkill (1995) recognized 60 species while Soladoye and Lewis (2003) recorded 60 species in Nigeria with over 60% abundance in the Northern region of the country with 27 species distributed across the ...