Download Tag: WISTAR ALBINO RATS


STUDIES ON THE EFFECT OF AQUEOUS EXTRACT OF MILLETTIA ABOENSIS LEAVES ON LOMOTIL–INDUCED CONSTIPATION IN WISTAR ALBINO RATS

ABSTRACT Millettia aboensis leaf is a rich source of reducing sugar, tannins, glycosides and flavonoids and has been reported to have medicinal property as well as some physiological potentials. The leaf also has been used by traditional herbalists for general healing of diseases including ulcer and laxatives. This study evaluated the effect of aqueous extract of M.  aboensis leaves on lomotil-induced constipation in Wistar albino rats. The qualitative phytochemical constituents ...

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ANTIDIARRHOEAL EFFECT OF UNRIPE Musa paradisiacae PULP AND PEEL HOMOGENATES ON CASTOR OIL-INDUCED DIARRHOEA IN WISTAR ALBINO RATS

ABSTRACT Musa paradisiacae commonly known as plantain is a rhizomatous perennial crop used as a source of starchy staple for millions of people in Nigeria. Different parts of the plant have been used in the treatment of various ailments and there are claims that it has antidiarrhoeal activity. This study is therefore aimed at determining the effects of unripe Musa paradisiacae pulp and peel homogenates on castor oil-induced diarrhoea in ...

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ANTI-ULCER ACTIVITY OF AQUEOUS TUBER EXTRACT OF Cyperus esculentus ON DICLOFENAC SODIUM AND HISTAMINE INDUCED GASTRIC LESIONS IN WISTAR ALBINO RATS

CHAPTER ONE INTRODUCTION Acid facilitates the digestion of protein and absorption of iron, calcium, and vitamin B-12 as well as preventsbacterial overgrowth and enteric infection (Schubert and Shamburek, 1990). However,when levels of acid (and pepsin) overwhelm mucosaldefense mechanisms ulcers occur.Peptic ulcer disease occurs mainly due to consumption of NSAIDS, infection by H. pylori, stress or due to pathological condition such as Zollinger-Ellison Syndrome (Mohammed et al., 2008).It has been shown ...

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ANTIULCEROGENIC AND IMMUNOSTIMULATORY PROPERTIES OF THE AQUEOUS EXTRACT OF THE LEAVES OF Ficus capensis IN WISTAR ALBINO RATS

ABSTRACT Ficuscapensis leaves have always played a great role in preventing, controlling and alleviating various disease conditions. This study was aimed at validating the traditional use of the leaves of Ficuscapensisin folk medicine as an anti- ulcer and immunostimulatory agent. Diclofenac sodium (100mg/kg) body weight was administered intraperitoneally to induce ulcer. Seven groups(five rats each)were used. Groups 2(150mg ranithidine),4,5,6and7 served as the ulcer test groups while group1 and 3 served ...

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