ANTI-ULCER ACTIVITY OF AQUEOUS TUBER EXTRACT OF Cyperus esculentus ON DICLOFENAC SODIUM AND HISTAMINE INDUCED GASTRIC LESIONS IN WISTAR ALBINO RATS
CHAPTER ONE INTRODUCTION Acid facilitates the digestion of protein and absorption of iron, calcium, and vitamin B-12 as well as preventsbacterial overgrowth and enteric infection (Schubert and Shamburek, 1990). However,when levels of acid (and pepsin) overwhelm mucosaldefense mechanisms ulcers occur.Peptic ulcer disease occurs mainly due to consumption of NSAIDS, infection by H. pylori, stress or due to pathological condition such as Zollinger-Ellison Syndrome (Mohammed et al., 2008).It has been shown ...
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